The Artists Helping Children Website

http://www.artistshelpingchildren.org/charityknittingforchildren.html

gives suggestions for numerous patterns to knit, crochet, or sew for children.

It does not appear as if Artists Helping Children directly receive or give the items.  You donate them on your own.  They do have lists for suggested hospitals and shelters.

Knit or crochet a teddy bear for a child in an area of the world where tradgey has struck.

 Futher information at: 

http://www.teddiesfortragedies.org/

Patterns for knitting or crocheting a teddy bear:

http://www.teddiesfortragedies.org/pattern.htm

Many Arms Reach You (M.A.R.Y.) project is a nonprofit organization collecting and distributing knitted, quilted, or crocheted blankets to disadvantaged mothers and their children.

Here are the guidelines and information on where to send if  you wish to make a blanket:

http://www.manyarms.org/guidelines.htm
 

from their website:

“ The Baby Pack Project  is a small charitable project aimed at providing under-privileged mothers of newborn babies on the lower south coast of Kwa Zulu Natal, South Africa, with a pack of the most basic items needed for a new born baby. ”

http://www.freewebs.com/babypackproject/index.htm

Make a “security blanket - snuggle” for a homeless animal:

http://www.snugglesproject.org/

You do NOT have to become a member to contribute. 

There are patterns avaiable on site for knitting, crochet or sewing here:

http://www.snugglesproject.org/patterns/ 

They also provide a link for you to find a participating shelter near you where you can donate your homemade items:

Where to find a participating shelter

“Purpose: Provide free knitted, crocheted, fleece/soft fabric hats for those who have lost their hair due to chemotherapy, brain surgery, burn wounds, etc. ” (quote from their site). 

For more information, how you can help, patterns on site:

http://headhuggers.org/